Cine Rex was a movie theatre in Antwerp, Belgium. It was located at De Keyserlei 15, and first opened in 1935. It was designed by Leon Stynen, a Belgian architect, modeled after large American movie theatres.<ref name=CT></ref>
When the Germans occupied Antwerp in 1940, during World War II, it was appropriated by the Germans and renamed the Eldorado. During the occupation, German-made films were shown.<ref name=CT/>
After liberation, it was restored to its original purpose. On 16 December 1944, at 15.20, a V-2 rocket hit the theatre during a showing of The Plainsman to an audience of approximately 1200 people. The attack killed 567 people including 296 Allied servicemen, making it the deadliest single V-2 attack.
The theatre was re-built in 1947, and by the 1950s. Cine Rex closed in 1993, and demolished in 1995.<ref name=CT/>